181. A Solution to the Anti-Bredt Olefin Synthesis Problem

Abstract PDF Supplementary Materials NEWSWEEK UCLA NEWSROOM Science | In the Pipeline NATURE C&E NEWS CHEMISTRY WORLD EARTH.COM IFL MSN YAHOO! NEWS

Luca McDermott,† Zach G. Walters,† Sarah A. French,‡ Allison M. Clark,‡ Jiaming Ding,‡ Andrew V. Kelleghan, K. N. Houk, and Neil K. Garg. Science 2024, 386, eadq3519.

180. Hydrosilylation of Propiolate Esters

Allison M. Clark, Giulianna Miseo, and Neil K. Garg. Org. Synth. 2024, Submitted.

179. Iridium-Catalyzed Borylation of Silanes

Christina A. Rivera, Benjamin A. Janda, and Neil K. Garg. Org. Synth. 2024, Submitted.

178. Enzymatic Saponification of Esters Containing β-Leaving Groups

Benjamin A. Janda, Allison M. Clark, and Neil K. Garg. Org. Synth. 2024, Submitted.

177. Organic Chemistry for Kids

ABSTRACT PDF

Arismel Tena Meza,† Laura G. Wonilowicz,† and Neil K. Garg. Nature Reviews Chemistry, 2024, 8, 715–716.

176. Fragment-Guided Genome Mining of Octacyclic Cyclophane Alkaloids from Fungi

ABSTRACT PDF Supporting Information

Yalong Zhang, Lin Wu, Tyler A. Kerr, Neil K. Garg, and Yi Tang. J. Am. Chem Soc. 2024, 146, 23933–23942.

175. Diels–Alder Cycloadditions of Oxacyclic Allenes and α-Pyrones

ABSTRACT PDF Supporting Information

Laura G. Wonilowicz,† Milauni M. Mehta,† Lisa L. Kamecke, Sarah A. French, and Neil K. Garg. Org. Lett. 2024, 26, 6465–6470.

174. Access to Complex Scaffolds Through [2+2] Cycloadditions of Strained Cyclic Allenes

ABSTRACT PDF Supporting Information

Matthew S. McVeigh,† Jacob P. Sorrentino,† Allison T. Hands, and Neil K. Garg. J. Am. Chem. Soc. 2024, 146, 15420–15427.



173. Total Synthesis of Lissodendoric Acid A

ABSTRACT PDF Supporting Information

Francesca M. Ippoliti,† Laura G. Wonilowicz,† Nathan J. Adamson, Evan R. Darzi, Joyann S. Donaldson, Daniel J. Nasrallah, Milauni M. Mehta, Andrew V. Kelleghan, K. N. Houk, and Neil K. Garg. Angew. Chem., Int. Ed. 2024, 63, e202406676.



172. Evaluation of Retro-Aldol vs Retro-Carbonyl-Ene Mechanistic Pathways in a Complexity Generating C–C Bond Fragmentation

ABSTRACT PDF Supporting Information

Ana S. Bulger, Daniel W. Turner, Qingyang Zhou, K. N. Houk, Neil K. Garg. Org. Lett. 2024, 26, 3602–3606.



171. Small Molecule Inhibition of RNA Binding Proteins in Haematologic Cancer

ABSTRACT PDF Supporting Information

Amit K. Jaiswal, Michelle L. Thaxton, Georgia M. Scherer, Jacob P. Sorrentino, Neil K. Garg and Dinesh S. Rao. RNA Biology 2024, 21, 1–14.



170. Enantioselective Nickel-Catalyzed Mizoroki–Heck Cyclization of Amide Electrophiles

ABSTRACT PDF Supporting Information

Ana S. Bulger,† Daniel J. Nasrallah,† Arismel Tena Meza,† and Neil K. Garg. Chem. Sci. 2024, 15, 2593–2600.



169. Hydration of Nitriles to Primary Amides Enabled by the Ghaffar-Parkins Catalyst

Abstract PDF

Daniel W. Turner, Allison T. Hands, and Neil K. Garg. Org. Synth. 2024, 101, 327–341

168. Difluoromethylation of Phenols

Abstract PDF

Allison T. Hands, Zach G. Walters, Jacob P. Sorrentino, and Neil K. Garg. Org. Synth. 2024, 101, 164–180.

167. Nickel-Catalyzed Amination of Aryl Chlorides

Abstract PDF

Zachary G. Walters, Daniel W. Turner, and Neil K. Garg. Org. Synth. 2024, 101, 150–163.

166. Generation and Reactivity of Unsymmetrical Strained Heterocyclic Allenes

Abstract Supporting Information Nat. Synth. News & Views

Andrew V. Kelleghan, Arismel Tena Meza, and Neil K. Garg. Nat. Synth. 2024, 3, 329–336.


165. Studies Pertaining to the Emerging Cannabinoid Hexahydrocannabinol (HHC)

Abstract PDF Supporting Information UCLA NEWSROOM Cannabis Health Politico Benzinga Labroots C&E News

Daniel J. Nasrallah and Neil K. Garg. ACS Chem. Biol. 2023, 18, 2023–2029.


164. Electrochemical Oxidation of Δ9-Tetrahydrocannabinol at Nanomolar Concentrations

Abstract PDF Supporting Information

Christina R. Forbes, Katie A. Spence, Neil K. Garg, and Evan R. Darzi. J. Org. Chem. 2023, 88, 11358–11362.


163. Facile Synthesis of 2-Aza-9,10-diphenylanthracene and the Effect of Precise Nitrogen Atom Incorporation on OLED Emitters Performance

Abstract PDF Supporting Information

Evan R. Darzi, Dane A. Stanfield, Luca McDermott, Andrew V. Kelleghan, Benjamin J. Schwartz, and Neil K. Garg. Mater. Adv. 2023, 4, 3351–3355.


162. Cyclic Allene Approach to the Manzamine Alkaloid Keramaphidin B

Abstract PDF Supporting Information Journal Cover

Milauni M. Mehta, Jordan A. M. Gonzalez, James L. Bachman, and Neil K. Garg. Org. Lett. 2023, 25, 5553–5557.


161. Total Synthesis of Phenanthroindolizidines Using Strained Azacyclic Alkynes

Abstract PDF Supporting Information

Katie A. Spence, Marie Hoffmann, and Neil K. Garg. Org. Lett. 2023, 25, 5044–5048.


160. Elucidating the Molecular Programming of a Nonlinear Non-Ribosomal Peptide Synthetase Responsible For Fungal Siderophore Biosynthesis

Abstract PDF Supporting Information

Matthew Jenner, Yang Hai, Hong H. Nguyen, Munro Passmore, Will Skyrud, Junyong Kim, Neil K. Garg, Wenjun Zhang, Rachel R. Ogorzalek Loo, and Yi Tang. Nat. Commun. 2023, 14, 2832–2843.


159. Catalyst-Controlled Annulations of Strained Cyclic Allenes with π-Allylpalladium Complexes

Abstract PDF Supporting Information

Dominick C. Witkowski, Matthew S. McVeigh, Georgia M. Scherer, Sarah M. Anthony, and Neil K. Garg. J. Am. Chem. Soc. 2023, 145, 10491–10496.


158. Strain-Promoted Reactions of 1,2,3-Cyclohexatriene and Its Derivatives

Abstract PDF Supporting Information Nature Perspective Chemistry World Nat. Synth. Highlight

Andrew V. Kelleghan,† Ana S. Bulger,† Dominick C. Witkowski, and Neil K. Garg. Nature 2023, 618, 748–754.


157. Total Synthesis of Lissodendoric Acid A via Stereospecific Trapping of a Strained Cyclic Allene

Abstract PDF Supporting Information Science Cover Science Perspective UCLA NEWSROOM C&E News SYNFACTS Synform Organic Chemistry Portal

Francesca M. Ippoliti,† Nathan J. Adamson,† Laura G. Wonilowicz, Daniel J. Nasrallah, Evan R. Darzi, Joyann S. Donaldson, and Neil K. Garg. Science 2023, 379, 261–265.

156. Synthesis of a Furoindoline Scaffold via an Interrupted Fischer Indolization

Abstract PDF

Georgia M. Scherer, Jordan Gonzalez, Laura G. Wonilowicz, and Neil K. Garg. Org. Synth. 2023, 100, 304–326.

155. A Cannabinoid Fuel Cell Capable of Producing Current by Oxidizing Δ9-Tetrahydrocannabinol

Abstract PDF Supporting Information UCLA Newsroom NBC News

Di Huang, Christina R. Forbes, Neil K. Garg, and Evan R. Darzi. Org. Lett. 2022, 24, 6705–6710.

154. A Symmetry-Driven Approach Toward the Total Synthesis of Dodecahedrane

Abstract PDF

Jason V. Chari,† Luca McDermott,† Jacob E. Dander, Bryan J. Simmons, and Neil K. Garg. Tetrahedron 2022, 126, 133041–133046. (Special issue in honor of Professor John Wood)

153. Mentoring is More Important than Ever

Abstract

Jennifer M. Heemstra and Neil K. Garg. Nature Reviews Chemistry 2022, in press.

152. Education Surges When Students Learn Together

Article

Neil K. Garg and Kevin D. Dougherty. Inside Higher Ed 2022, published online May 25, 2022.

151. Merging Metals and Strained Intermediates

Abstract PDF

Katie A. Spence,† Arismel Tena Meza,† and Neil K. Garg. Chem Catalysis 2022, 2, 1870–1879.

150. Gaming Stereochemistry

Abstract PDF

Francesca M. Ippoliti, Melinda M. Nguyen, Amber J. Reilly, and Neil K. Garg. Nature Reviews Chemistry 2022, 6, 373–374.

149. π-Extension of heterocycles via a Pd-catalyzed heterocyclic aryne annulation: π-extended donors for TADF emitters

Abstract PDF

Katie A. Spence,† Jason V. Chari,† Mattia Di Niro, Robert B. Susick, Narcisse Ukwitegetse, Peter I. Djurovich, Mark E. Thompson, and Neil K. Garg. Chem. Sci. 2022, 13, 5884–5892.

148. Advancing Global Chemical Education Through Interactive Teaching Tools

Abstract PDF

Francesca M. Ippoliti,† Jason V. Chari,† and Neil K. Garg. Chem. Sci. 2022, 13, 5790–5796.

147. Catalysis in Modern Drug Discovery: Insights from a Graduate Student-Taught Undergraduate Course

Abstract PDF

Jason V. Chari,† Rachel R. Knapp,† Timothy B. Boit, and Neil K. Garg. J. Chem. Educ. 2022, 99, 1296–1303.

146. Interception of 1,2-Cyclohexadiene with TEMPO Radical

Abstract PDF

Matthew S. McVeigh and Neil K. Garg. Tetrahedron Lett. 2021, 87, 153539–153543

145. A Convenient Method for the Removal of Tetrabutylammonium Salts from Desilylation Reactions

Abstract PDF

Luca McDermott, Dominick C. Witkowski, and Neil K. Garg. Org. Synth. 2022, 99, 53–67.

144. Synthesis of Phenanthridinones via the Palladium-Catalyzed Annulation of Benzyne

Abstract PDF

Dominick C. Witkowski, Luca McDermott, and Neil K. Garg. Org. Synth. 2022, 99, 159–173.

143. Synthesis of Carboxylic Acids from Benzamide Precursors Using Nickel Catalysis

Abstract PDF

Ana S. Bulger, Dominick C. Witkowski, and Neil K. Garg. Org. Synth. 2022, 99, 305–325.

142. Cell-Free Total Biosynthesis of Plant Terpene Natural Products using an Orthogonal Cofactor Regeneration System

Abstract PDF Supporting Information

Undramaa Bat-Erdene, John M. Billingsley, William C. Turner, Benjamin R. Lichman, Francesca M. Ippoliti, Neil K. Garg, Sarah E. O’Connor, and Yi Tang. ACS Catal. 2021, 11, 9898–9903.

141. Cycloaddition Cascades of Strained Alkynes and Oxadiazinones

Abstract PDF Supporting Information

Melissa Ramirez, † Evan Darzi, † Joyann Donaldson, Kendall N. Houk, Neil K. Garg. Angew. Chem., Int. Ed. 2021, 60, 18201–18208.

140. Leveraging Fleeting Strained Intermediates to Access Complex Scaffolds

Abstract PDF

Sarah M. Anthony, Laura G. Wonilowicz,† Matthew S. McVeigh,† and Neil K. Garg* JACS Au 2021, 1, 897–912.

139. Palladium-Catalyzed Annulations of Strained Cyclic Allenes

Abstract PDF Supporting Information

Andrew V. Kelleghan, Dominick C. Witkowski, Matthew S. McVeigh, Neil K. Garg. J. Am. Chem. Soc. 2021, 143, 25, 9338–9342.

138. A Platform for On-the-Complex Annulation Reactions with Transient Aryne Intermediates

Abstract PDF Supporting Information

Jason V. Chari,† Katie A. Spence,† Robert B. Susick, and Neil K. Garg. Nat. Commun. 2021, 12, 3706.

137. Total Synthesis of (−)-Strictosidine and Interception of Aryne Natural Product Derivatives “Strictosidyne” and “Strictosamidyne”

Abstract PDF Supporting Information

Sarah M. Anthony,† Veronica Tona,† Yike Zou,† Lucas A. Morrill, John M. Billingsley, Megan Lim, Yi Tang,* K. N. Houk,* Neil K. Garg* J. Am. Chem. Soc. 2021, 143, 10, 7471–7479.

136. Origins of Endo Selectivity in Diels–Alder Reactions of Cyclic Allene Dienophiles

Abstract PDF Supporting Information

Melissa Ramirez, Dennis Svatunek, Fang Liu, Neil K. Garg, and K. N. Houk. Angew. Chem., Int. Ed. 2021, 60, 14989–14997.

135. Palladium-Catalyzed Acetylation of Arylbromides

Abstract PDF

Milauni M. Mehta, Andrew V. Kelleghan, and Neil K. Garg. Org. Synth. 2021, 98, 68-83

134. Taming Radical Pairs in the Crystalline Solid State: Discovery and Total Synthesis of Psychotriadine

Abstract PDF Supporting Information JACS Spotlight & ACS EDITORS CHOICE UCLA News

Jordan J. Dotson, Ieva Liepuoniute, J. Logan Bachman, Vince M. Hipwell, Saeed I. Khan, K. N. Houk*, Neil K. Garg*, and Miguel A. Garcia-Garibay.* J. Am. Chem. Soc. 2021, 143, 10, 4043–4054.

133. The Adult Organic Coloring Book

Available at Amazon

Jacob E. Dander,† Evan R. Darzi,† and Neil K. Garg

132. Cyanoamidine Cyclization Approach to Remdesivir’s Nucleobase

Abstract PDF OPR&D Highlights

Rachel R. Knapp,† Veronica Tona,† Taku Okada, Richmond Sarpong, and Neil K. Garg. Org. Lett. 2020, 22, 8430–8435.

131. Reductive Arylation of Amides via a Nickel‐Catalyzed Suzuki–Miyaura Coupling and Transfer Hydrogenation Cascade

Abstract PDF Supporting Information

Timothy Boit,† Milauni M. Mehta,† Junyong Kim, Emma L. Baker, and Neil K. Garg. Angew. Chem., Int. Ed. 2021, 60, 2472–2477

130. Activation of C–O and C–N Bonds Using Non-Precious-Metal Catalysis

Abstract PDF

Timothy Boit,† Ana, S. Bulger,† Jacob E. Dander,† and Neil K. Garg. ACS Catalysis 2020, 10, 12109–12126.

129. An Enzymatic Alder-Ene Reaction

Abstract PDF Supporting Information C&E News Phys.org Synfacts Highlight

Masao Ohashi, Cooper S. Jamieson, Yujuan Cai, Dan Tan, Daiki Kanayama, Man-Cheng Tang, Sarah M. Anthony, Jason V. Chari, Joyann S. Barber, Elias Picazo, Thomas B. Kakule, Shugeng Cao, Neil K. Garg, Jiahai Zhou, K. N. Houk, and Yi Tang. Nature 2020, 586, 64–69.

128. Intercepting Fleeting Cyclic Allenes with Asymmetric Nickel Catalysis

Abstract PDF Supporting Information C&E News SYNFACTS HIGHLIGHT

Michael M. Yamano,† Andrew V. Kelleghan,† Qianzhen Shao,† Maude Giroud, Bryan J. Simmons, Bo Li, Shuming Chen, K. N. Houk, and Neil K. Garg. Nature 2020, 586, 242–247.

127. The Organic Coloring Book: Cheesy Goes to the Doctor

Available at Amazon

Kaylie Garg,† Elaina Garg,† and Neil K. Garg.

126. Putting Mentoring First

Article

Jen Heemstra and Neil Garg. Chemical & Engineering News 2020, 98, (https://cen.acs.org/careers/employment/Putting-mentoring-first/98/i35).

125. Treating a Global Health Crisis with a Dose of Synthetic Chemistry

Abstract PDF

Melissa A. Hardy, Brandon A. Wright, J. Logan Bachman, Timothy B. Boit, Hannah M. S. Haley, Rachel R. Knapp, Robert F. Lusi, Taku Okada, Veronica Tona, Neil K. Garg*, and Richmond Sarpong.* ACS Cent. Sci. 2020, 6, 1017–1030.

124. Discovery and Total Synthesis of a Bis(Cyclotryptamine) Alkaloid Bearing the Elusive Piperidinoindoline Scaffold

Abstract PDF Supporting Information JACS Spotlight

Jordan J. Dotson, J. Logan Bachman, Miguel A. Garcia-Garibay, Neil K. Garg. J. Am. Chem. Soc. 2020, 142, 11685–11690.

123. Silyl Tosylate Precursors to Cyclohexyne, 1,2-Cyclohexadiene, and 1,2-Cycloheptadiene

Abstract PDF Supporting Information

Matthew S. McVeigh, Andrew V. Kelleghan, Michael M. Yamano, Rachel R. Knapp, and Neil K. Garg. Org. Lett. 2020, 22, 4500–4504. 

122. Evaluation of the photodecarbonylation of crystalline ketones for the installation of reverse prenyl groups on the pyrrolidinoindoline scaffold

Abstract PDF

Jordan J. Dotson, Neil K. Garg, and Miguel A. Garcia Garibay. Tetrahedron 2020, 76, 131181.

121. Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the Treatment of Alzheimer’s Disease

Abstract PDF Supporting Information

Tina Bilousova, Bryan J. Simmons, Rachel R. Knapp, Chris J. Elias, Jesus Campagna, Mikhail Melnik, Sujyoti Chandra, Samantha Focht, Chunni Zhu, Kanagasabai Vadivel, Barbara Jagodzinska, Whitaker Cohn, Patricia Spilman, Karen H. Gylys, Neil K. Garg, and Varghese John. ACS Chem. Biol. 2020, 15, 1671–1684.

120. Electrochemical Oxidation of Δ9-Tetrahydrocannabinol: A Simple Strategy for Marijuana Detection

Abstract PDF Supporting Information Phys.org EurekAlert! (AAAS) ScienceDaily Chemicals Market News Psych Congress Network/Addiction Professional Medical Dialogues News-Medical.net L.A. Cannabis News ScienceBlog Technology Networks Lab Manager ABC Science Show UCLA Newsroom

Evan R. Darzi and Neil K. Garg. Org. Lett. 2020, 22, 3951–3955

119. Nickel-Catalyzed Conversion of Amides to Carboxylic Acids

Abstract PDF Supporting Information Chemistry Views OPR&D Highlights Organic Chemistry Portal Organic Chemistry Portal – Functional Group Protection

Rachel R. Knapp, Ana S. Bulger, and Neil K. Garg. Org. Lett. 2020, 22, 2833–2837.

118. Safety Assessment of Benzyne Generation from a Silyl Triflate Precursor

Abstract PDF Supporting Information

Andrew V. Kelleghan, Carl A. Busacca, Max Sarvestani, Ivan Volchkov, Jose M. Medina, Neil K. Garg. Org. Lett. 2020, 22, 1665–1669.

117. From Heavy Water to Heavy Aldehydes

Abstract PDF

Sarah M. Anthony, Andrew V. Kelleghan, Milauni M. Mehta, and Neil K. Garg. Nature Catal. 2019, 2, 1058–1059.

116. From Glovebox to Benchtop

Abstract PDF

Timothy B. Boit, Katie A. Spence, and Neil K. Garg. Nature Catal. 2020, 3, 2–3.

115. Ni-Catalyzed Suzuki–Miyaura Cross-Coupling of Aliphatic Amides on the Benchtop

Abstract PDF Supporting Information

Milauni M. Mehta,† Timothy B. Boit,† Jacob E. Dander,† and Neil K. Garg. Org. Lett. 2020, 22, 1–5. 

114. Total Synthesis as a Vehicle for Collaboration

Abstract PDF

Lucas A. Morrill†, Robert B. Susick†, Jason V. Chari, and Neil K. Garg. J. Am. Chem. Soc. 2019, 141, 12423–12443.

113. How Organic Chemistry Became One of UCLA’s Most Popular Classes

PDF

Neil K. Garg. J. Biol. Chem. 2019, 294, 17678–17683.

112. Synthesis of Triphenylene via the Palladium-catalyzed Annulation of Benzyne

Abstract PDF

Katie A. Spence, Milauni M. Mehta, and Neil K. Garg. Org. Synth. 2022, 99, 174–189.

111. Synthesis of 2,5-Diaryloxadiazinones

Abstract PDF

Andrew V. Kelleghan, Katie A. Spence, and Neil K. Garg. Org. Synth. 2020, 97, 189–206.

110. Base-Mediated Meerwein–Ponndorf–Verley Reduction of Aromatic and Heterocyclic Ketones

Abstract PDF Supporting Information

Timothy B. Boit, Milauni M. Mehta and Neil K. Garg. Org. Lett. 2019, 21, 6447–6451

109. Chemoenzymatic Conversion of Amides to Enantioenriched Alcohols in Aqueous Medium

Abstract PDF Supporting Information Nature Chemistry Community

Jacob E. Dander, Maude Giroud, Sophie Racine, Evan R. Darzi, Oscar Alvizo, David Entwistle, and Neil K. Garg. Communications Chemistry 2019, 2, 82.

108. Cyclic Alkyne Approach to Heteroatom-Containing Polycyclic Aromatic Hydrocarbon Scaffolds

Abstract PDF SYNFACTS HIGHLIGHT

Evan R. Darzi, Joyann S. Barber, and Neil K. Garg. Angew. Chem., Int. Ed. 2019, 58, 9419–9424.

107. Thioesterase-Catalyzed Aminoacylation and Thiolation of Polyketides in Fungi

Abstract PDF Supporting Information

Man-Cheng Tang, Curt R. Fischer, Jason V. Chari, Dan Tan, Sundari Suresh, Angela Chu, Molly Miranda, Justin Smith, Zhuan Zhang, Neil K. Garg, Robert P. St. Onge, and Yi Tang. J. Am. Chem. Soc. 2019, 141, 8198–8206.

106. Cycloadditions of Oxacyclic Allenes and a Catalytic Asymmetric Entryway to Enantioenriched Cyclic Allenes

Abstract PDF Supporting Information

Michael M. Yamano, Rachel R. Knapp, Aurapat Ngamnithiporn, Melissa Ramirez, Kendall N. Houk,* Brian M. Stoltz,* and Neil K. Garg. Angew. Chem., Int. Ed. 2019, 58, 5653–5657.

105. A Concise Approach to Cyclohexyne and 1,2-Cyclohexadiene Precursors

ABSTRACT PDF SUPPORTING INFORMATION

Jason Chari,† Francesca Ippoliti,† and Neil K. Garg. J. Org. Chem. 2019, 84, 3652–3655.

104. Breaking Amide C–N Bonds in an Undergraduate Organic Chemistry Laboratory

Abstract PDF Supporting Information

Jacob E. Dander, Lucas A. Morrill, Melinda M. Nguyen, Shuming Chen, and Neil K. Garg. J. Chem. Ed. 2019, 96, 776–780.

103. Facile Reduction of Amides Using Nickel Catalysis: Reduction of 12-Aminododecanolactam

Abstract PDF

Bryan J. Simmons, Melissa Ramirez, and Neil K. Garg. Org. Synth. 2019, 96, 436–454.

102. Synthesis of 8-Hydroxygeraniol

Abstract PDF

Francesca M. Ippoliti, Joyann S. Barber, and Neil K. Garg. Org. Synth. 2019, 96, 586–598.

101. Synthesis of Fused Indolines by Interrupted Fischer Indolization in a Microfluidic Reactor

Abstract PDF Supporting Information

Alexander Tuan-Huy Duong, Bryan J. Simmons, Mohammad Parvez Alam, Jesus Campagna, Neil K. Garg, Varghese John. Tetrahedron Lett. 2019, 60, 322–326.

100. Canvass: A Crowd-Sourced, Natural Product Screening Library for Exploring Biological Space

Abstract PDF Supporting Information Chemistry World Highlight

Sara E. Kearney, Gergely Zahoránszky-Kőhalmi, Kyle R. Brimacombe, Mark J. Henderson, Caitlin Lynch, Tongan Zhao, Kanny K. Wan, Zina Itkin, Christopher Dillon, Min Shen, Dorian M. Cheff, Tobie D. Lee, Danielle Bougie, Ken Cheng, Nathan P. Coussens, Dorjbal Dorjsuren, Richard T. Eastman, Ruili Huang, Michael J. Iannotti, Surendra Karavadhi, Carleen Klumpp-Thomas, Jacob S. Roth, Srilatha Sakamuru, Wei Sun, Steven A. Titus, Adam Yasgar, Ya-Qin Zhang, Jinghua Zhao, Rodrigo B. Andrade, M. Kevin Brown, Noah Z. Burns, Jin K. Cha, Emily E. Mevers, Jon Clardy, Jason A. Clement, Peter A. Crooks, Gregory D. Cuny, Jake Ganor, Jesus Moreno, Lucas A. Morrill, Elias Picazo, Robert B. Susick, Neil K. Garg, Brian C. Goess, Robert B. Grossman, Chambers C. Hughes, Jeffrey N. Johnston, Madeleine M. Joullié, A. Douglas Kinghorn, David G.I. Kingston, Michael J. Krische, Ohyun Kwon, Thomas J. Maimone, Susruta Majumdar, Katherine N. Maloney, Enas Mohamed, Brian T. Murphy, Pavel Nagorny, David E. Olson, Larry E. Overman, Lauren E. Brown, John K. Snyder, John A. Porco, Jr., Fatima Rivas, Samir A. Ross, Richmond Sarpong, Indrajeet Sharma, Jared T. Shaw, Zhengren Xu, Ben Shen, Wei Shi, Corey Stephenson, Alyssa L. Verano, Derek S. Tan, Yi Tang, Richard E. Taylor, Regan J. Thomson, David A. Vosburg, Jimmy Wu, William M. Wuest, Armen Zakarian, Yufeng Zhang, Tianjing Ren, Zhong Zuo, James Inglese, Sam Michael, Anton Simeonov, Wei Zheng, Paul Shinn, Ajit Jadhav, Matthew B. Boxer, Matthew D. Hall, Menghang Xia, Rajarshi Guha, and Jason M. Rohde. ACS Central Science 2018, 4, 1727–1741.

99. Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki-Miyaura and Negishi Cross-Coupling Reactions for Tetra-ortho Substituted Biaryl Synthesis.

Abstract PDF Supporting Information

Nitinchandra Dahyabhai Patel, Joshua D. Sieber, Sergei Tcyrulnikov, Bryan J. Simmons, Daniel Rivalti, Krishnaja Duvvuri, Yongda Zhang, Donghong A. Gao, Keith R. Fandrick, Nizar Haddad, Kendricks So Lao, Hari Prasad Reddy Mangunuru, Soumik Biswas, Bo Qu, Nelu Grinberg, Scott Pennino, Heewon Lee, Jinhua J. Song, B. Frank Gupton, Neil K. Garg, Marisa C. Kozlowski, and Chris H. Senanayake. ACS Catal. 2018, 8, 10190–10209.

98. Empowering Students to Innovate: Engagement in Organic Chemistry Teaching.

Abstract PDF

Neil K. Garg. Angew. Chem. Int. Ed. 2018, 57, 15612–15613.

97. Diels–Alder Cycloadditions of Strained Azacyclic Allenes

Abstract PDF Supporting Information C&E News SYNFACTS HIGHLIGHT OPR&D HIGHLIGHT

Joyann S. Barber,† Michael M. Yamano,† Melissa Ramirez, Evan R. Darzi, Rachel R. Knapp, Fang Liu, K. N. Houk, and Neil K. Garg. Nat. Chem. 2018, 10, 953–960.

96. Synthesis of 8-Hydroxygeraniol

Abstract PDF Supporting Information

Francesca M. Ippoliti,† Joyann S. Barber,† Yi Tang, and Neil K. Garg. J. Org. Chem. 2018, 83, 11323–11326.

95. Smart Access to 3D Structures

Abstract PDF

 Johnny Dang, Brian Lin, Julia Yuan, Schawn T. Schwartz, Rishabh M. Shah, and Neil K. Garg. Nature Reviews Chemistry 2018, 2, 95-96.

94. Arynes and Cyclic Alkynes as Synthetic Building Blocks for Stereodefined Quaternary Centers

Abstract PDF Supporting Information

Elias Picazo,† Sarah M. Anthony,† Maude Giroud, Adam Simon, Margeaux A. Miller, K. N. Houk, and Neil K. Garg. J. Am. Chem. Soc. 2018, 140, 7605–7610.

93. Enantioselective Total Syntheses of Methanoquinolizidine-Containing Akuammiline Alkaloids and Related Studies

Abstract PDF Supporting Information Organic Chemistry Portal

Elias Picazo,† Lucas A. Morrill,† Robert B. Susick, Jesus Moreno, Joel M. Smith, and Neil K. Garg. J. Am. Chem. Soc. 2018, 140, 6483–6492.

92. Shining a Light on Amine Synthesis

Abstract PDF

Joyann S. Barber,† Francesca M. Ippoliti,† and Neil K. Garg. Nature Catal. 2018, 1, 97–98.

91. Nickel-Catalyzed Suzuki–Miyaura Coupling of Aliphatic Amides

Abstract PDF Supporting Information SYNFACTS HIGHLIGHT

Timothy B. Boit,† Nicholas A. Weires,† Junyong Kim,† and Neil K. Garg. ACS Catal. 2018, 8, 1003–1008.

90. Nickel-Catalyzed Transamidation of Aliphatic Amide Derivatives

Abstract PDF Supporting Information

Jacob E. Dander,† Emma L. Baker,† and Neil K. Garg. Chem. Sci. 2017, 8, 6433–6438.

89. Understanding and Interrupting the Fischer Azaindolization Reaction

Abstract PDF Supporting Information


Bryan J. Simmons, Marie Hoffmann, Pier Alexandre Champagne, Elias Picazo, Katsuya Yamakawa, Lucas A. Morrill, K. N. Houk, and Neil K. Garg. J. Am. Chem. Soc. 2017, 139, 14833–14836.

88. Engineering the Biocatalytic Selectivity of Iridoid Production in Saccharomyces cerevisiae

Abstract PDF Supporting Information

John M. Billingsley, Anthony B. DeNicola, Joyann S. Barber, Man-Cheng Tang, Joe Horecka, Angela Chu, Neil K. Garg, and Yi Tang. Metab. Eng. 2017, 44, 117–125.

87. Spectroscopy 101: A Practical Introduction to Spectroscopy and Analysis for Undergraduate Organic Chemistry Laboratories

Abstract PDF Supporting Information

Lucas A. Morrill, Jacquelin K. Kammeyer, and Neil. K. Garg. J. Chem. Educ. 2017, 94, 1584–1586.

86. Conjugated Trimeric Scaffolds Accessible from Indolyne Cyclotrimerizations: Synthesis, Structures, and Electronic Properties

Abstract PDF Supporting Information Synfacts Highlight

Janice B. Lin, Tejas K. Shah, Adam E. Goetz, Neil K. Garg, and K. N. Houk. J. Am. Chem. Soc. 2017, 139, 10447–10455.

85. Indole Diterpenoid Natural Products as the Inspiration for New Synthetic Methods and Strategies

Abstract PDF

Michael A. Corsello,† Junyong Kim,† and Neil K. Garg. Chem. Sci. 2017, 8, 5836–5844.

84. Total Synthesis of (–)-Tubingensin B Enabled by the Strategic Use of an Aryne Cyclization

Abstract PDF Supporting Information Synfacts Highlight

Michael A. Corsello,† Junyong Kim,† and Neil K. Garg. Nat. Chem. 2017, 9, 944–949.

83. Enantioselective Nickel-Catalyzed Mizoroki–Heck Cyclizations to Generate Quaternary Stereocenters

Abstract PDF Supporting Information

Jean-Nicolas Desrosiers, Jialin Wen, Sergei Tcyrulnikov, Soumik Biswas, Bo Qu, Liana Hie, Dmitry Kurouski, Ling Wu, Nelu Grinberg, Nizar Haddad, Carl A. Busacca, Nathan K. Yee, Jinhua J. Song, Neil K. Garg, Xumu Zhang, Marisa C. Kozlowski, and Chris H. Senanayake. Org. Lett. 2017, 19, 3338–3341.

82. Kinetic Modeling of the Nickel-Catalyzed Esterification of Amides

Abstract PDF Supporting Information C&E News ACS Editor’s Choice (June 4, 2017)

Nicholas A. Weires, Daniel D. Caspi, and Neil K. Garg. ACS Catal. 2017, 7, 4381–4385.

80. The Organic Coloring Book

Available at Amazon AVAILABLE IN SPANISH C&E News Lab Out Loud

Elaina Garg, Kaylie Garg, and Neil K. Garg

79. Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases

Abstract PDF Supporting Information

Michio Sato, Jacob E. Dander, Chizuru Sato, Yiu-sun Hung, Shu-Shan Gao, Man-Cheng Tang, Leibniz Hang, Jaclyn M. Winter, Neil K. Garg, Kenji Watanabe, and Yi Tang. J. Am. Chem. Soc. 2017, 139, 5317–5320.

78. Nickel-Catalyzed Reduction of Secondary and Tertiary Amides

Abstract PDF Supporting Information Organic Chemistry Portal

Bryan J. Simmons, Marie Hoffmann, Jaeyeon Hwang, Moritz K. Jackl, and Neil K. Garg. Org. Lett. 2017, 19, 1910–1913.

77. Enzyme-Catalyzed Stereoselective Intramolecular Hydroalkoxylation

Abstract PDF Supporting Information SYNFACTS Highlight

Shu-Shan Gao, Marc Garcia-Borràs, Joyann S. Barber, Yang Hai, Abing Duan, Neil K. Garg, K. N. Houk, and Yi Tang. J. Am. Chem. Soc. 2017, 139, 3639–3642.

76. Organic Chemistry Can Sizzle

Abstract PDF

Tejas K. Shah, and Neil K. Garg. Nat. Rev. Chem. 2017, 1, 1–3.

75. Breaking Amides Using Nickel Catalysis

Abstract PDF

Jacob E. Dander and Neil K. Garg. ACS Catal. 2017, 7, 1413–1423.

74. Expanding the ROMP Toolbox: Synthesis of Air-Stable Benzonorbornadiene Polymers by Aryne Chemistry

Abstract PDF Supporting Information

Jose M. Medina, Jeong Hoon Ko, Heather D. Maynard, and Neil K. Garg. Macromolecules 2017, 50, 580–586.

73. Pardon the Interruption: A Modification of Fischer’s Venerable ­Reaction for the Synthesis of Heterocycles and Natural Products

Abstract PDF

Robert B. Susick,† Lucas A. Morrill,† Elias Picazo,† and Neil K. Garg. Synlett 2017, 28, 1–11.

72. Nickel-Catalyzed Esterification of Aliphatic Amides

Abstract PDF Supporting Information

Liana Hie,† Emma L. Baker,† Sarah M. Anthony, Jean-Nicolas Desrosiers, Chris Senanayake, and Neil K. Garg. Angew. Chem. Int. Ed. 2016, 55, 15129–15132.

81. Mizoroki–Heck Cyclizations of Amide Derivatives for the Introduction of Quaternary Centers

Abstract PDF Supporting Information

Jose M. Medina,† Jesus Moreno,† Sophie Racine, Shuaijing Du, and Neil K. Garg. Angew. Chem., Int. Ed. 2017, 56, 6567–6571.

71. Nickel-Catalyzed Suzuki-Miyaura Coupling in t-Amyl Alcohol for the Preparation of 5-(Furan-3-yl)pyrimidine

Abstract PDF

Liana Hie and Neil K. Garg. Org. Synth. 2016, 93, 306–318.

70. Quantification of the Electrophilicity of Benzyne and Related Intermediates

Abstract PDF Supporting Information

Noah F. Fine Nathel,† Lucas A. Morrill,† Herbert Mayr, and Neil K. Garg. J. Am. Chem. Soc. 2016, 138, 10402–10405

69. Construction of Quaternary Stereocenters via Nickel-Catalyzed Heck Cyclizations

Abstract PDF Supporting Information

Jean-Nicolas Desrosiers, Liana Hie, Soumik Biswas, Olga V. Zatolochnaya, Sonia Rodriguez, Heewon Lee, Nelu Grinberg, Nizar Haddad, Nathan K. Yee, Neil K. Garg, and Chris H. Senanayake. Angew. Chem. Int. Ed. 2016, 55, 11921–11924

68. Benchtop Delivery of Ni(cod)2 using Paraffin Capsules

Abstract PDF Supporting Information

Jacob E. Dander,† Nicholas A. Weires,† and Neil K. Garg. Org. Lett. 2016, 18, 3934–3936

67. A Two-Step Approach to Achieve Secondary Amide Transamidation Enabled by Nickel Catalysis

Abstract PDF Supporting Information

Emma L. Baker, Michael M. Yamano, Yujing Zhou, Sarah M. Anthony, and Neil K. Garg. Nat. Commun. 2016, 7, 1–5

66. Nickel-Catalyzed Alkylation of Amide Derivatives

Abstract PDF Supporting Information

Bryan J. Simmons,† Nicholas A. Weires,† Jacob E. Dander, and Neil K. Garg. ACS Catal. 2016, 6, 3176–3179

65. Expanding the Strained Alkyne Toolbox: Generation and Utility of Oxygen-Containing Strained Alkynes

Abstract PDF Supporting Information

Tejas K. Shah,† Jose M. Medina,† and Neil K. Garg. J. Am. Chem. Soc. 2016, 138, 4948–4954

64. P450-Mediated Coupling of Indole Fragments to Forge Communesin and Unnatural Isomers

Abstract PDF Supporting Information

 Hsiao-Ching Lin, Travis C. McMahon, Ashay Patel, Michael Corsello, Adam Simon, Wei Xu, Muxun Zhao, K. N. Houk, Neil K. Garg, and Yi Tang. J. Am. Chem. Soc. 2016, 138, 4002–4005

63. Synthetic Studies Pertaining to the 2,3-Pyridyne and 4,5-Pyrimidyne

Abstract PDF Supporting Information

Jose M. Medina, Moritz K. Jackl, Robert B. Susick, and Neil K. Garg. Tetrahedron 2016, 72, 3629–3634

62. Nitrone Cycloadditions of 1,2-Cyclohexadiene

Abstract PDF Supporting Information

Joyann S. Barber, Evan D. Styduhar, Hung V. Pham, Travis C. McMahon, K. N. Houk, and Neil K. Garg.  J. Am. Chem. Soc. 2016, 138, 2512–2515

61. Enantioselective Total Syntheses of Akuammiline Alkaloids (+)-Strictamine, (–)-2(S)-Cathafoline, and (–)-Aspidophylline A

Abstract PDF Supporting Information SynFacts Highlight

Jesus Moreno,† Elias Picazo,† Lucas A. Morrill, Joel M. Smith, and Neil K. Garg. J. Am. Chem. Soc. 2016, 138, 1162–1165

60. Nickel-Catalyzed Activation of Acyl C–O Bonds of Methyl Esters

Abstract PDF Supporting Information

Liana Hie, Noah F. Fine Nathel, Xin Hong, Yun-Fang Yang, K. N. Houk, and Neil K. Garg. Angew. Chem. Int. Ed. 2016, 55, 2810–2814

59. Nickel-Catalysed Suzuki–Miyaura Coupling of Amides

Abstract PDF Supporting Information C&E News C&E News Top Research of 2015

Nicholas A. Weires, Emma L. Baker and Neil K. Garg. Nat. Chem. 2016, 8, 75–79

58. Discovery of Unclustered Fungal Indole Diterpene Biosynthetic Pathways through Combinatorial Pathway Reassembly in Engineered Yeast

Abstract PDF Supporting Information


Man-Cheng Tang, Hsiao-Ching Lin, Dehai Li, Yi Zou, Jian Li, Wei Xu, Ralph A. Cacho, Maureen E. Hillenmeyer, Neil K. Garg, and Yi Tang. J. Am. Chem. Soc. 2015, 137, 13724–13727

57. Conversion of Amides to Esters by the Nickel-Catalysed Activation of Amide C–N Bonds

Abstract PDF Supporting Information C&E News Nat. Chem. Highlight Angew. Chem. Int. Ed. Highlight Synform C&E News Top Research of 2015 Org. Chem. Highlights

Liana Hie, Noah F. Fine Nathel, Tejas K. Shah, Emma L. Baker, Xin Hong, Yun-Fang Yang, Peng Liu, K. N. Houk, and Neil K. Garg. Nature 2015, 524, 79–83

56. Fischer Indolizations as a Strategic Platform for the Total Synthesis of Picrinine

Abstract PDF Supporting Information

Joel M. Smith, Jesus Moreno, Ben W Boal, and Neil K. Garg. J. Org. Chem. 2015, 80, 8954–8967. (Featured Article)

55. Generation and Regioselective Trapping of a 3,4-Piperidyne for the Synthesis of Functionalized Heterocycles

Abstract PDF Supporting Information JACS Spotlight C&E News

Travis C. McMahon,† Jose M. Medina,† Yun-Fang Yang, Bryan J. Simmons, K. N. Houk, and Neil K. Garg. 
J. Am. Chem. Soc. 2015, 137, 4082–4085

54. Elucidation of the Concise Biosynthetic Pathway of the Communesin Indole Alkaloids

Abstract PDF

Hsiao-Ching Lin, Grace Chiou, Yit-Heng Chooi, Travis C. McMahon, Wei Xu, Neil K. Garg, and Yi Tang. 
Angew. Chem. Int. Ed. 2015, 54, 3004–3007. (Selected as a Very Important Paper)

53. Computational Predictions of Substituted Benzyne and Indolyne Regioselectivities

Abstract PDF

Elias Picazo, K. N. Houk, and Neil K. Garg. Tetrahedron Lett. 2015, 56, 3511–3514. (Special issue for Professor Harry Wasserman)

52. Synthetic Chemistry Fuels Interdisciplinary Approaches to the Production of Artemisinin

Abstract PDF

Michael A. Corsello, and Neil K. Garg. Nat. Prod. Rep. 2015, 32, 359–366

51. Pyridynes and Indolynes as Building Blocks for Functionalized Heterocycles and Natural Products

Abstract PDF 

Adam E. Goetz, Tejas K. Shah and Neil K. Garg. Chem. Commun. 2015, 51, 34–45. (Featured Article)

50. The Role of Aryne Distortions, Steric Effects, and Charges on Regioselectivities in Aryne Reactions

Abstract PDF Supporting Information

Jose M. Medina,† Joel L. Mackey,† Neil K. Garg, and K. N. Houk. J. Am. Chem. Soc. 2014, 136, 15798–15805

49. Total Synthesis of (–)-N-Methylwelwitindolinone B Isothiocyanate via a Chlorinative Oxabicycle Ring-Opening Strategy

Abstract PDF Supporting Information Synfacts Highlight

Nicholas A. Weires,† Evan D. Styduhar,† Emma L. Baker, and Neil K. Garg. J. Am. Chem. Soc. 2014, 136, 14710–14713

48. Cycloadditions of Cyclohexynes and Cyclopentyne

Abstract PDF Supporting Information

Jose M. Medina,† Travis C. McMahon,† Gonzalo Jiménez-Osés, K. N. Houk, and Neil K. Garg. J. Am. Chem. Soc. 2014, 136, 14706–14709

47. Cascade Reactions: A Driving Force in Akuammiline Alkaloid Total Synthesis

Abstract PDF

Joel M. Smith,† Jesus Moreno,† Ben W. Boal, and Neil K. Garg. Angew. Chem. Int. Ed. 2015, 54, 400–412

46. Nickel-Catalyzed Amination of Aryl Chlorides and Sulfamates in 2-Methyl-THF

Abstract PDF Supporting Information C&E News

Noah F. Fine Nathel, Junyong Kim, Liana Hie, Xingyu Jiang, and Neil K. Garg. ACS Catal. 2014, 4, 3289–3293

45. Nickel-Catalyzed Suzuki–Miyaura Cross-Coupling in a Green Alcohol Solvent for an Undergraduate Organic Chemistry Laboratory

Abstract PDF Supporting Information

Liana Hie, Jonah J. Chang, and Neil K. Garg. J. Chem. Educ. 2015, 92, 571–574

44. Total Synthesis of the Akuammiline Alkaloid Picrinine

Abstract PDF Supporting Information Synfacts Highlight

Joel M. Smith, Jesus Moreno, Ben W. Boal, and Neil K. Garg. J. Am. Chem. Soc. 2014, 136, 4504–4507

43. Concise Enantiospecific Total Synthesis of Tubingensin A

Abstract PDF Supporting Information Synfacts Highlight | Organic Chemistry Portal

Adam E. Goetz,† Amanda L. Silberstein,† Michael A. Corsello, and Neil K. Garg. J. Am. Chem. Soc. 2014, 136, 3036–3039

42. Total Syntheses of Indolactam Alkaloids (–)-Indolactam V, (–)-Pendolmycin, (–)-Lyngbyatoxin A, and (–)-Teleocidin A-2

Abstract PDF Supporting Information

Noah F. Fine Nathel,† Tejas K. Shah,† Sarah M. Bronner, and Neil. K. Garg. Chem. Sci. 2014, 5, 2184–2190

41. Enabling the Use of Heterocyclic Arynes in Chemical Synthesis

Abstract PDF

Adam E. Goetz and Neil K. Garg. J. Org. Chem. 2014, 79, 846–851

40. Palladium-Catalyzed Acetylation of Arenes

Abstract PDF Supporting Information C&E News Organic Chemistry Portal

Stephen D. Ramgren and Neil K. Garg. Org. Lett. 2014, 16, 824–827

39. Enantiospecific Total Synthesis of N-Methylwelwitindolinone D Isonitrile

Abstract PDF Supporting Information Synfacts Highlight

Evan D. Styduhar, Alexander D. Huters, Nicholas A. Weires, and Neil K. Garg. Angew. Chem. Int. Ed. 2013, 52, 12422–12425

38. Nickel-Catalyzed Suzuki-Miyaura Coupling in Green Solvents

Abstract PDF Supporting Information Nexus Newsletters

Stephen D. Ramgren, Liana Hie, Yuxuan Ye, and Neil K. Garg. Org. Lett. 2013, 15, 3950–3953

37. Expanding the Structural Diversity of Polyketides by Exploring the Cofactor Tolerance of an Inline Methyltransferase Domain

Abstract PDF Supporting Information

Jaclyn M. Winter, Grace Chiou, Ian R. Bothwell,, Wei Xu, Neil K. Garg, Minkui Luo, and Yi Tang. Org. Lett. 2013, 15, 3774–3777

36. EcdGHK are Three Tailoring Iron Oxygenases for Amino Acid Building Blocks of the Echinocandin Scaffold

Abstract PDF Supporting Information

Wei Jiang, Ralph A. Cacho, Grace Chiou, Neil K. Garg, Yi Tang, and Christopher T. Walsh. J. Am. Chem. Soc. 2013, 135, 4457–4466

35. Synthesis of Diphenylhexatriene by the Pd-Catalyzed Dimerization of Cinnamyl Acetate

Abstract PDF Supporting Information

Tehetena Mesganaw, G.-Yoon J. Im, and Neil K. Garg. J. Org. Chem. 2013, 78, 3391–3393

34. Regioselective Reactions of 3,4-Pyridynes Enabled by the Aryne Distortion Model

Abstract PDF Supporting Information Synfacts Highlight

Adam E. Goetz and Neil K. Garg. Nat. Chem. 2013, 5, 54–60

33. Ni- and Fe-Catalyzed Cross-Coupling Reactions of Phenol Derivatives

Abstract PDF

Tehetena Mesganaw and Neil K. Garg. Org. Process Res. Dev. 2013, 17, 29–39

32. Identification and Characterization of the Chaetoviridin and Chaetomugilin Gene Cluster in Chaetomium globosum Reveal Dual Functions of an Iterative Highly-Reducing Polyketide Synthase

Abstract PDF Supporting Information

Jaclyn M. Winter, Michio Sato, Satoru Sugimoto, Grace Chiou, Neil K. Garg, Yi Tang, and Kenji Watanabe. 
J. Am. Chem. Soc. 2012, 134, 17900–17903

31. Interrupted Fischer Indolization Approach toward the Communesin Alkaloids and Perophoramidine

Abstract PDF Supporting Information

Alex W. Schammel, Grace Chiou, and Neil K. Garg. Org. Lett. 2012, 14, 4556–4559

30. Steric Effects Compete with Aryne Distortion to Control Regioselectivities of Nucleophilic Additions to 3-Silylarynes

Abstract PDF Supporting Information

Sarah M. Bronner, Joel L. Mackey, K. N. Houk, and Neil K. Garg. J. Am. Chem. Soc. 2012, 134, 13966–13969

29. Nickel-Catalyzed Amination of Aryl Sulfamates and Carbamates Using an Air-Stable Precatalyst

Abstract PDF Supporting Information

Liana Hie, Stephen D. Ramgren, Tehetena Mesganaw, and Neil K. Garg. Org. Lett. 2012, 14, 4182–4185

28. Iron-Catalyzed Alkylations of Aryl Sulfamates and Carbamates

Abstract PDF Supporting Information Synfacts Highlight | Organic Chemistry Portal

Amanda L. Silberstein, Stephen D. Ramgren, and Neil K. Garg. Org. Lett. 2012, 14, 3796–3799

27. Cine Substitution of Arenes Using the Aryl Carbamate as a Removable Directing Group

Abstract PDF Supporting Information

Tehetena Mesganaw, Noah F. Fine Nathel, and Neil K. Garg. Org. Lett. 2012, 14, 2918–2921

26. Total Syntheses of the Elusive Welwitindolinones with Bicyclo[4.3.1]cores

Abstract PDF

Alexander D. Huters, Evan D. Styduhar, and Neil K. Garg. Angew. Chem. Int. Ed. 2012, 51, 3758–3765

25. An Efficient Computational Model to Predict the Synthetic Utility of Heterocyclic Arynes

Abstract PDF Supporting Information

Adam E. Goetz, Sarah M. Bronner, Jordan D. Cisneros, Joshua M. Melamed, Robert S. Paton, K. N. Houk, and Neil K. Garg. Angew. Chem. Int. Ed. 2012, 51, 2758–2762

24. Total Synthesis of Oxidized Welwitindolinones and (–)-N-Methylwelwitindolinone C Isonitrile

Abstract PDF Supporting Information

Kyle W. Quasdorf, Alexander D. Huters, Michael W. Lodewyk, Dean J. Tantillo, and Neil K. Garg. J. Am. Chem. Soc. 2012, 134, 1396–1399

23. Synthesis of (+)-Phenserine using an Interrupted Fischer Indolization Reaction

Abstract PDF Supporting Information

Alex W. Schammel, Grace Chiou, Neil K. Garg. J. Org. Chem. 2012, 77, 725–728

22. Total Synthesis of (–)-N-Methylwelwitindolinone C Isothiocyanate

Abstract PDF Supporting Information C&E News Highlight Synfacts Highlight Nature Chemistry Organic Chemistry Portal

Alexander D. Huters, Kyle W. Quasdorf, Evan D. Styduhar, and Neil K. Garg. J. Am. Chem. Soc. 2011, 133, 15797–15799

21. Understanding and Modulating Indolyne Regioselectivities

Abstract PDF

Sarah M. Bronner, Adam E. Goetz, and Neil K. Garg. Synlett 2011, 18, 2599–2604. (invited SYNPACTS article)

20. Nickel-Catalyzed Amination of Aryl Carbamates and Sequential Site-Selective Cross-Couplings

Abstract PDF Supporting Information

Tehetena Mesganaw, Amanda L. Silberstein, Stephen D. Ramgren, Noah F. Fine Nathel, Xin Hong, Peng Liu, and Neil K. Garg. Chem. Sci. 2011, 2, 1766–1771

19. Total Synthesis of (±)-Aspidophylline A

Abstract PDF Supporting Information Synfacts Highlight Org. Highlights

Liansuo Zu, Ben W. Boal, and Neil K. Garg. J. Am. Chem. Soc. 2011, 133, 8877–8879

18. Suzuki–Miyaura Cross-Coupling of Aryl Carbamates and Sulfamates: Experimental and Computational Studies

Abstract PDF Supporting Information Synfacts Highlight

Kyle W. Quasdorf, Aurora Antoft-Finch, Peng Liu, Amanda L. Silberstein, Anna Komaromi, Tom Blackburn, Stephen D. Ramgren, K. N. Houk, Victor Snieckus, and Neil K. Garg. J. Am. Chem. Soc. 2011, 133, 6352–6363

17. Why Do Some Fischer Indolizations Fail?

Abstract PDF Supporting Information

Nihan Çelebi-Olcüm, Ben W. Boal, Alexander D. Huters, Neil K. Garg, and K. N. Houk. J. Am. Chem. Soc. 2011, 133, 5752–5755

16. Overturning Indolyne Regioselectivities and Synthesis of Indolactam V

Abstract PDF Supporting Information Synpacts Highlight

Sarah M. Bronner, Adam E. Goetz, and Neil K. Garg. J. Am. Chem. Soc. 2011, 133, 3832–3835

15. A Fungal Nonribosomal Peptide Synthetase Module that can Synthesize Thiopyrazines

Abstract PDF Supporting Information

Kangjian Qiao, Hui Zhou, Wei Xu, Wenjun Zhang, Neil K. Garg, and Yi Tang. Org. Lett. 2011, 13, 1758–1761

14. Nickel-Catalyzed Amination of Aryl Sulfamates

Abstract PDF Supporting Information Synfacts Highlight

Stephen D. Ramgren, Amanda L. Silberstein, Yang Yang, and Neil K. Garg. Angew. Chem. Int. Ed. 2011, 50, 2171–2173

13. Nickel-Catalyzed Cross-Couplings Involving Carbon–Oxygen Bonds

Abstract PDF

Brad M. Rosen, Kyle W. Quasdorf, Daniella A. Wilson, Na Zhang, Ana-Maria Resmerita, Neil K. Garg, and Virgil Percec. Chem. Rev. 2011, 111, 1346–1416 (invited contribution)

12. Indoles and Indolizidines in Heterocycles in Natural Product Synthesis

Sarah M. Bronner, G-Yoon J. Im, and Neil K. Garg; K. C. Majumdar and S. K. Chattopadhyay, Eds.; Wiley–VCH, 2011

11. Indolyne Experimental and Computational Studies: Synthetic Applications and Origins of Selectivities of Nucleophilic Additions

Abstract PDF Supporting Information

G-Yoon J. Im, Sarah M. Bronner, Adam E. Goetz, Robert S. Paton, Paul H.-Y. Cheong, K. N. Houk, and Neil K. Garg. J. Am. Chem. Soc. 2010, 132, 17933–17944

10. Bis(tricyclohexylphosphine)dichloronickel

Abstract PDF

Kyle W. Quasdorf and Neil K. Garg. Encyclopedia of Reagents for Organic Synthesis, 2010 (invited contribution)

9. Synthetic Studies Inspired by Vinigrol

Abstract PDF

Alexander D. Huters and Neil K. Garg. Chem. Eur. J. 2010, 16, 8586–8595

8. Exploration of the Interrupted Fischer Indolization Reaction

Abstract PDF Supporting Information

Alex W. Schammel, Ben W. Boal, Liansuo Zu, Tehetena Mesganaw, and Neil K. Garg. Tetrahedron 2010, 66, 4687–4695. (Special issue for Professor Brian Stoltz’s receipt of the Tetrahedron Young Investigator Award)

7. Indolyne and Aryne Distortions and Nucleophilic Regioselectivities

Abstract PDF Supporting Information Chemistry World Highlight

Paul H.-Y. Cheong, Robert S. Paton, Sarah M. Bronner, G-Yoon J. Im, Neil K. Garg, and K. N. Houk. J. Am. Chem. Soc. 2010, 132, 1267–1269.

6. Suzuki–Miyaura Coupling of Aryl Carbamates, Carbonates, and Sulfamates

Abstract PDF Supporting Information Synfacts Highlight

Kyle W. Quasdorf, Michelle Riener, Krastina V. Petrova, and Neil K. Garg. J. Am. Chem. Soc. 2009, 131, 17748–17749

5. Efficient Synthesis of 2-(Trimethylsilyl)phenyl Trifluoromethanesulfonate: A Versatile Precursor to o-Benzyne

Abstract PDF Supporting Information ACS Noteworthy Chemistry Highlight

Sarah M. Bronner and Neil K. Garg. J. Org. Chem. 2009, 74, 8842–8843

4. An Interrupted Fischer Indolization Approach Toward Fused Indoline-Containing Natural Products

Abstract PDF Supporting Information

Ben W. Boal, Alex W. Schammel, and Neil K. Garg. Org. Lett. 2009, 11, 3458–3461

3. Concise Synthesis of the Bicyclic Scaffold of N-Methylwelwitindolinone C Isothiocyanate via an Indolyne Cyclization

Abstract PDF Supporting Information

Xia Tian, Alexander D. Huters, Colin J. Douglas, and Neil K. Garg. Org. Lett. 2009, 11, 2349–2351

2. Indolynes as Electrophilic Indole Surrogates: Fundamental Reactivity and Synthetic Applications

Abstract PDF Supporting Information

Sarah M. Bronner, Kevin B. Bahnck, and Neil K. Garg. Org. Lett. 2009, 11, 1007–1010

1. Cross-Coupling Reactions of Aryl Pivalates with Boronic Acids

Abstract PDF Supporting Information Synfacts Highlight

Kyle W. Quasdorf, Xia Tian, and Neil K. Garg. J. Am. Chem. Soc. 2008, 130, 14422–14423

13. Total Synthesis of (–)-Sarain A.

Abstract PDF Supporting Information

Michael H. Becker, Peter Chua, Robert Downham, Christopher J. Douglas, Neil K. Garg, Sheldon Hiebert, Stefan Jaroch, Richard T. Matsuoka, Joy A. Middleton, Fay W. Ng, and Larry E. Overman. J. Am. Chem. Soc. 2007, 129, 11987–12002.

12. Total Synthesis of (–)-Sarain A.

Abstract PDF Synfacts Highlight

Neil K. Garg, Sheldon Hiebert, and Larry E. Overman. Angew. Chem. Int. Ed. 2006, 45, 2912–2915.

11. The Utility of the Classical and Oxidative Heck Reactions in Natural Product Synthesis: Studies Toward the Total Synthesis of Dragmacidin F.

Abstract PDF

Neil K. Garg, Daniel D. Caspi, and Brian M. Stoltz. Synlett (Special Issue) 2006, 3081–3087.

10. Effects of a Modified Dye-Labeled Nucleotide Spacer Arm on Incorporation by Thermophilic DNA Polymerases.

Abstract PDF

Christopher J. Lacenere, Neil K. Garg, Brian M. Stoltz, and Stephen R. Quake. Nucleosides, Nucleotides & Nucleic Acids 2006, 25, 9–15.

9. A Unified Synthetic Approach to the Pyrazinone Dragmacidins.

Abstract PDF

Neil K. Garg and Brian M. Stoltz. Chem. Commun. (Feature Article) 2006, 3769–3779.

8. The Total Synthesis of Dragmacidins D and F. Neil K. Garg, Ph.D. Thesis, California Institute of Technology, March 2005.
7. A Ligand-Free Solid-Supported System for Sonogashira Couplings: Applications in Nucleoside Chemistry.

Abstract PDF Supporting Information

Neil K. Garg, Carolyn C. Woodroofe, Christopher J. Lacenere, Stephen R. Quake, and Brian M. Stoltz. Chem. Commun. 2005, 4551–4553.

6. Heterogeneous Reductive Isomerization Reaction Using Catalytic Pd/C and H2.

Abstract PDF Supporting Information

Daniel D. Caspi, Neil K. Garg, and Brian M. Stoltz. Org. Lett. 2005, 7, 2513–2516.

5. Development of an Enantiodivergent Strategy for the Total Synthesis of (+)- and (–)-Dragmacidin F from a Single Enantiomer of Quinic Acid.

Abstract PDF Supporting Information

Neil K. Garg, Daniel D. Caspi, and Brian M. Stoltz. J. Am. Chem. Soc. 2005, 127, 5970–5978.

4. The Formal Total Synthesis of Dragmacidin B, trans-Dragmacidin C, and cis- and trans-Dihydrohamacanthins A.

Abstract PDF

Neil K. Garg and Brian M. Stoltz. Tetrahedron Lett. 2005, 46, 2423–2426.

3. Synthesis of Bis(indole)-1,2,4-Triazinones.

Abstract PDF

Neil K. Garg and Brian M. Stoltz. Tetrahedron Lett. 2005, 46, 1997–2000.

2. The Total Synthesis of (+)-Dragmacidin F.

Abstract PDF Supporting Information

Neil K. Garg, Daniel D. Caspi, and Brian M. Stoltz. J. Am. Chem. Soc. 2004, 126, 9552–9553.

1. The First Total Synthesis of Dragmacidin D.

Abstract PDF Supporting Information

Neil K. Garg, Richmond Sarpong, and Brian M. Stoltz. J. Am. Chem. Soc. 2002, 124, 13179–13184.